Business challenges
1、 Mechanical performance verification of dissolution instrument;
2、 Selection and exploration of dissolution methods with differentiated force;
3、 Comparison of dissolution curves between the original preparation and the imitated preparation in vitro.
service content
Dissolution is a functional evaluation parameter of oral solid preparations, which is an effective research method to evaluate the quality of preparations in vitro and judge the efficacy of drugs. Dissolution is a process in which the solid preparation undergoes disintegration and the drug dissolves in the dissolution medium in molecular state. Disintegration is an early method to evaluate whether a drug is effective or not. Later, it was found that a drug with good disintegration has no efficacy. The problem is that after disintegration, the drug does not dissolve. In order to better evaluate the therapeutic effect of drugs in vitro, the dissolution determination method was developed in the later stage.
Tablet / hard capsule
1. Disintegration time limit test;
2. Formulation of solubility pH curve;
3. Dissolution / release measurement;
4. Formulation of multiple dissolution curves.
Our strengths
1、 In China, we have a high-level GMP compliance service laboratory, and passed the FDA site audit and local management structure audit in June 2015.
2、 In China, we have high-quality related equipment, such as multiple Sortex dissolution instruments, Sortex solvent compounding instruments, multiple matching HPLC and UV testers, to meet various types of dissolution curve research.
